Palatin WKN: A3DTUW ISIN: US6960775020 Kürzel: PTN Forum: Aktien User: allesaufaurora
1,104 EUR
+4,05 %+0,043
28. Nov, 22:58:47 Uhr,
L&S Exchange
Kommentare 570
K
Kaig11,
Montag 18:08 Uhr
0
Mit dem Begriff Kosmetik hab ich bei PLT kein Problem das trifft es ganz gut. Wenn man sich nur mal die letzten vier Wochen anschaut, gabs öfters mal +15 bis +25%, um dann einen Tag später wieder ebenso stark zu korrigieren.
M
Michael4772,
Montag 16:51 Uhr
0
Ist der Kursanstieg nicht nur Kosmetik? Palatin benötigt doch Geld...in ein paar Tagen geben sie dann neue Aktien aus
K
Kaig11,
Montag 16:48 Uhr
0
Aber man sollte immer direkt auf der HP von PLT schauen. Da steht heute:
“Our objective is to out-license the UC program. At this stage, there has been significant interest in and ongoing discussions around our UC program from multiple parties.”
Ulcerative colitis is a form of inflammatory bowel disease (IBD) that causes inflammation in the digestive tract and can result in damage to the colon lining.2 Patients often experience a range of unpredictable symptoms that impact their daily lives, such as abdominal pain, bloody stool and urgency to use the bathroom.2,3 The disease course varies between patients, and in some cases can lead to surgery or complications, including cancer or death.3,4
Orally administered PL8177 targets melanocortin-1 receptors on the luminal surface of colon epithelial cells. In a Phase 1 clinical study, the oral formulation successfully demonstrated sustained delivery of PL8177 to the lumen of the colon with no systemic exposure.
The Phase 2 PL8177 study is a multi-center, randomized, double-blind, placebo-controlled, adaptive design, parallel group of PL8177, with once daily (QD) oral dosing in adult UC subjects for 8 weeks. The study was originally designed to enroll up to 28 adult subjects with active UC from multiple sites, with an interim analysis planned after completion of 12-16 subjects. Due to the strategic decision to out-license the UC program at an earlier stage, Palatin decided to end enrollment after 13 subjects. The efficacy evaluations and endpoints are in line with the latest FDA Draft Guidance for Industry: Ulcerative Colitis: Developing Drugs for Treatment (April 2022), including the primary efficacy endpoint measurement, the Mayo Endoscopic Subscore, which evaluates the level of disease in the colon mucosa. Additional trial information, including inclusion and exclusion criteria, can be found at https://clinicaltrials.gov/ via the identifier NCT05466890.
The Company’s Phase 2 trial in UC builds upon presented preclinical data from a series of oral PL8177 dose-ranging studies in the dextran sulfate sodium (DSS) colon inflammation model, which showed significant improvements in inflamed colon health, including relative increases in colon cells needed for a healthy colon. PL8177 treatment showed clear evidence of resolving pathological inflammation by repolarizing colon macrophages from a pro-inflammatory to a pro-inflammation resolving state.
K
Kaig11,
Montag 16:46 Uhr
0
Hier ist so gut wie nix zu erfahren
M
A
ACP,
18. Nov 8:36 Uhr
0
We believe the pharmacological treatment of obesity is in the early stages of a multiyear cycle of innovation and will have a market value greater than $100 billion per year. We do have large companies that are very interested in the dry eye disease programs and then we have -- as well as the glaucoma and retinal.
So it may be a mixture. You may see a out-licensing of dry eye disease and then a corporate -- and a corporate combination of assets for the others that are a little bit earlier. Our expectation, not Nostradamus-confirmed, is that we're going to have multiple deals as we go forward. And some of them could be absolutely as early as the first quarter of next year.
A
ACP,
18. Nov 8:30 Uhr
0
As of September 30, 2024, Palatin's cash and cash equivalents were $2.4 million. Palatin did receive a scheduled $2.5 million deferred payment in November 2024 from Cosette Pharmaceuticals related to the sale of Vyleesi. Obviously, since this was received in November, it is not included in our September 30 cash and cash equivalents balance. Future investment and activities will be focused and limited to our core programs in obesity. We've retained an investment bank to conduct, explore and evaluate strategic options for our non-obesity programs. At this stage, there is significant interest in and ongoing discussions for our Phase III dry eye disease program, our early-stage glaucoma and retina development programs and our Phase II ulcerative colitis program from multiple parties.
M
c
Checker666,
2. Okt 8:33 Uhr
0
https://www.gurufocus.com/news/2539968/palatin-technologies-inc-ptn-q4-2024-earnings-call-transcript-highlights-strategic-moves-and-financial-performance
c
cabal06ba,
1. Okt 13:39 Uhr
0
"Palatin’s net loss for the quarter and fiscal year ended June 30, 2024, was $8.6 million and $29.7 million, or $(0.51) and $(2.02) per basic and diluted common share, respectively, compared to a net loss of $9.8 million and $24.0 million, or $(0.84) and $(2.21) per basic and diluted common share, respectively, for the same periods in 2023.
The decrease in net loss for the quarter ended June 30, 2024, over the quarter ended June 30, 2023, was mainly due to the decrease in Vyleesi operating expenses, offset by the elimination of net product revenue of Vyleesi and the recognition of the change in fair value of warrant liabilities for the quarter ended June 30, 2023.
The increase in net loss for the fiscal year ended June 30, 2024, over the prior fiscal year, was mainly due to the recognition of an income tax benefit related to the sale of New Jersey Net Operating Losses, and the recognition of a gain on purchase commitments for the fiscal year ended June 30, 2023."
c
cabal06ba,
1. Okt 13:34 Uhr
0
https://palatin.com/press_releases/palatin-reports-fourth-quarter-and-fiscal-year-ended-2024-financial-results-provides-update-on-clinical-programs-strategic-priorities-and-anticipated-milestones/
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