APELLIS PHARMACT.DL-,0001 WKN: A2JAAW ISIN: US03753U1060 Kürzel: APLS Forum: Aktien Thema: Hauptdiskussion
But safety issues persist. Earlier this month, the American Society of Retina Specialists posted a notice that a small number of patients experienced eye inflammation called occlusive vasculitis after receiving a Syfovre injection. "While the second-quarter number was strong, we think the rate of serious retinal vasculitis safety concerns will remain a dominant overhang on the stock over the next several months as investors await more safety updates and more clarity on likely causes," Stringer said. On today's stock market, APLS stock plummeted 19.6% to close at 25.75. Seven Total Cases, Company Says Since Syfovre's launch, seven patients have experienced retinal vasculitis, Apellis said in a news release. That includes four occlusive cases, meaning patients lost some of their vision. Each incident occurred seven to 13 days following the first injection, Needham's Stringer said. To date, two of those seven have recovered their vision. Two patients still have severe visual impairment and three cases are still evolving. So far, Apellis has shipped 68,000 vials of Syfovre. "Some vial returns have occurred, but management characterized the number as 'very small,' " Stringer said. "Management surveyed retinal specialists from July 20-22. About one-third plan to use Syfovre in new and treated patients, one-third plan to use in treated patients only and about one-third plan to pause use until further safety info is available."
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